Thursday 13 December 2018

LSD was made by Eli Lilly Pharaceutical company

found this Eli Lilly was making LSD like substances in the 1950's than produced first antidepressant Prozac..both stimulating 5HT serotinergic neurons..
Lysergic acid 2-butyl amide (2-Butyllysergamide, LSB) is an analogue of LSD originally developed by Richard Pioch at Eli Lilly in the 1950s,[1] but mostly publicised through research conducted by the team led by David E. Nichols at Purdue University. It is a structural isomer of LSD, with the two ethyl groups on the amide nitrogen having been replaced by a single sec-butyl group, joined at the 2-position.[2] It is one of the few lysergamide derivatives to exceed the potency of LSD in animal drug discrimination assays, with the (R) isomer having an ED50 of 33nmol/kg for producing drug-appropriate responding, vs 48nmol/kg for LSD itself. The corresponding (R)-2-pentyl analogue has higher binding affinity for the 5-HT1A and 5-HT2A receptors, but is less potent in producing drug-appropriate responding, suggesting that the butyl compound has a higher efficacy at the receptor target.[3] The drug discrimination assay for LSD in rats involves both 5-HT1A and 5-HT2A mediated components, and while lysergic acid 2-butyl amide is more potent than LSD as a 5-HT1A agonist, it is slightly less potent as a 5-HT2A agonist, and so would probably be slightly less potent than LSD as a hallucinogen in humans. The main use for this drug has been in studies of the binding site at the 5-HT2A receptor through which LSD exerts most of its pharmacological effects,[4] with the stereoselective activity of these unsymmetric monoalkyl lysergamides foreshadowing the subsequent development of compounds such as lysergic acid 2,4-dimethylazetidide (LSZ). ref wikipedia, lsd eli lilly

Saturday 8 December 2018

US Bilderberg Group Attendees

U.S. BILDERBERG GROUP ATTENDEE'S:
United States Edit
Thomas E. Donilon (2012),[3] Executive Vice President for Law and Policy at Fannie Mae (1999–2005), National Security Advisor (2010 – 2013)
Roger Altman (2011, 2012, 2013),[2][11][108] Deputy Treasury Secretary from 1993–1994, Founder and Chairman of Evercore Partners
George W. Ball (1954, 1993),[109] Under Secretary of State 1961–1968, Ambassador to U.N. 1968 (deceased)
Sandy Berger (1999),[110] National Security Advisor, 1997–2001
Hillary Clinton (1997),[111] First Lady of the USA when attending, later 67th United States Secretary of State
Timothy Geithner (2008, 2009),[2][108] Treasury Secretary
Dick Gephardt (2012),[3] former Congressman and House Majority Leader
Lee H. Hamilton (1997), former Congressman[citation needed]
Christian Herter,[112] (1961, 1963, 1964, 1966), 53rd United States Secretary of State (deceased)
Charles Douglas Jackson (1957, 1958, 1960),[113] Special Assistant to the President (deceased)
Joseph E. Johnson[114] (1954), President Carnegie Endowment for International Peace (deceased)
Henry Kissinger (1957, 1964, 1966, 1971, 1973, 1974, 1977, 2008, 2009, 2010,[21] 2011, 2012,[3] 2013,[11] 2015[13]),[78][115] 56th United States Secretary of State
Mark G. Mazzie (1986, 1987),[3] Chief of Staff, The Honorable George C. Wortley, U.S. House of Representatives.
Richard Perle (2011), Chairman of the Defense Policy Board Advisory Committee 2001–2003, United States Assistant Secretary of Defense 1981–1987[34]
Colin Powell (1997), 65th United States Secretary of State[citation needed]
Condoleezza Rice (2008),[2] 66th United States Secretary of State[original research?]
George P. Shultz (2008),[2] 60th United States Secretary of State[original research?]
Lawrence Summers,[108] Director of the National Economic Council
Paul Volcker (2010),[108] Chair of the President's Economic Recovery Advisory Board and Chairman of the Federal Reserve from 1979–1987
Terry Wolfe (2010),[21] author and former Assistant Secretary of Defense for International Security Affairs
Robert Zoellick (2008–2015),[2][3][10][11][12][13][21][50] former Trade Representative, former Deputy Secretary of State and former President of the World Bank Group
H.R. McMaster (2017), U.S. National Security Advisor, 2017–, and Lieutenant General.[116]
Wilbur Ross (2017), United States Secretary of Commerce,2017–[116]
Presidents Edit
George H. W. Bush (1989, 1992)[citation needed]
Bill Clinton (1991),[102][103] President 1993–2001
Gerald Ford (1964, 1966),[14][117] President 1974–1977 (deceased)
Senators Edit
Tom Daschle (2008),[2] Senator from South Dakota 1987-2005
John Edwards (2004),[118][119] Senator from North Carolina 1999–2005
Chuck Hagel (1999, 2000),[120] Senator from Nebraska 1997–2009, Secretary of Defense 2013–2015.
John Kerry (2012),[3] 68th United States Secretary of State and Senator from Massachusetts (1985–2013)
Sam Nunn (1996, 1997), Senator from Georgia 1972–1997[citation needed]
Lindsey Graham (2016), Senator from South Carolina since 2003[citation needed]
Governors Edit
Mitch Daniels (2012)[121] Governor of Indiana 2004–2013
Jon Huntsman, Jr. (2012),[3] Governor of Utah 2005–2009
Rick Perry (2007),[122] Governor of Texas 2000–2015
Mark Sanford (2008),[123] Governor of South Carolina 2003–2011
Kathleen Sebelius (2008),[2] Governor of Kansas 2003-2009, Secretary of Health and Human Services 2009-2014.
Mark Warner (2005), Governor of Virginia 2002-2006, Senator from Virginia assumed office January 3, 2009